- Z-Mount Lens/FX Format
- Aperture Range: f/4.5 to f/40
- Six Super ED and Two ED Glass Elements
- ARNEO and Nano Crystal Coatings
- Multi-Focus Stepping Motor AF System
- Vibration Reduction Image Stabilization
- Programmable Control Ring
- Inner Balance Technology
- Information OLED Panel and L.Fn Button
- Weather-Sealed Design, Fluorine Coating

Featuring a combination of two Super ED and six ED glass elements, chromatic aberrations and color fringing is effectively eliminated throughout the zoom range for notable clarity and colour accuracy. ARNEO and Nano Crystal Coats are used to prevent ghosting, reflections, and flare in order to realize improved contrast and clarity when working in strong lighting and backlit conditions. The Nano Crystal Coat controls incidental light from a diagonal direction while the ARNEO Coat controls incidental light from a vertical direction.

Multi-focus system incorporates two separate AF drive units, which are synchronized, to deliver especially fast and accurate focusing throughout the zoom range. This system uses stepping motors, which offer impressively smooth and quiet autofocus performance that is well-suited to both stills and video applications. Full-time manual focus override is also possible and an internal focusing design is used, where only the internal lens groups are moved during focusing, to maintain the overall length of the lens during use and to promote faster focusing speeds.

Short zoom throw rotation of just 80° permits quick changing between the 100mm to the 400mm positions. Updated zoom design prevents lens creep, regardless if the lens is pointing straight up or down, without having to adjust torque or tension settings.

- Nikon NIKKOR Z 100-400mm f/4.5-5.6 VR S Lens
- LC-77B Lens Cap
- Nikon LF-N1 Rear Lens Cap
- Nikon HB-103 Lens Hood
- CL-C3 Lens Case