- 24.5MP FX-Format BSI CMOS Sensor
- EXPEED 6 Image Processing Engine
- UHD 4K30 Video; N-Log & 10-Bit HDMI Out
- Multi-CAM 3500 II 51-Point AF System

This sensor also enables a wide sensitivity range from ISO 100-51200, which can be expanded to ISO 50-204800, along with a quick 7 fps shooting rate with the viewfinder or 12 fps in live view. This sensor also permits UHD 4K video recording up to 30 fps using either full-frame or cropped areas. Full HD recording up to 120 fps is available, too, along with integrated N-Log Gamma and HLG settings for refined color control.

Complementing the imaging, when working with the viewfinder, a 51-point phase-detection autofocus system is available, which includes 15 cross-type points for greater accuracy in low-light conditions. When working in live view or recording video, a 273-point Hybrid AF system is used that blends on-sensor phase-detection points and a contrast-detection system for quick performance and excellent subject tracking, including support for Eye-Detection AF.

At its core, the D780 relies on the familiarity and tradition of a DSLR, including a 0.7x-magnification pentaprism optical viewfinder, along with a large 3.2" 2.36m-dot tilting touchscreen LCD. Dual UHS-II SD memory card slots offer flexible storage and built-in Wi-Fi and Bluetooth also enable wireless file transferring along with remote camera control from a mobile device.

- Nikon D780 DSLR Camera (Body Only)
- Nikon EN-EL15b Rechargeable Lithium-Ion Battery
- Nikon MH-25A Battery Charger for EN-EL15 Li-Ion Battery
- Nikon UC-E24 USB Cable
- AN-DC21 Strap
- Nikon BF-1B Body Cap
- Nikon DK-5 Eyepiece Cap
- DK-31 Rubber Eyecup